Date of Award
Master of Science in Engineering (MSE)
Chemical and Materials Engineering
Emanuel A. Waddell
C. P. Chen
Microfluidics., Miniature electronic equipment., Microfluidic devices., Microelectronics., Micromechanics., Biochips., Biotechnology--Materials.
The purpose of the research was to construct a working lab-on-a-chip device constructed from polydimethylsiloxane (PDMS) in a Y-channel design that consisted of two generated magnetic fields: one localized below the channel, and an external field outside of the device generated through two rare earth magnets. The external field provided a method to attract the superparamagnetic beads while the localize field influenced attractive and replusive forces in the channel. The localized magnetic field allowed for controlling the direction the superparamagnetic beads in the channel to a predetermined well. The localized magnetic field generated a field of 5.7 x 10-3 mT. The fluid flow within the device was electroosmotically driven. The electroosmotic flow in the channel was 3.13x10-7 cm2/V s. The superparamagnetic bead traveled down the channel at 8.98 x 10-5 m/s. Beads were identified with Raman spectroscopy.
Lechuga, Diana C., "Separation of superparamagnetic beads with dual magnetic fields" (2013). Theses. 12.