Date of Award


Document Type


Degree Name

Master of Science in Engineering (MSE)


Chemical and Materials Engineering

Committee Chair

Emanuel A. Waddell

Committee Member

Krishnan Chittur

Committee Member

C. P. Chen


Microfluidics., Miniature electronic equipment., Microfluidic devices., Microelectronics., Micromechanics., Biochips., Biotechnology--Materials.


The purpose of the research was to construct a working lab-on-a-chip device constructed from polydimethylsiloxane (PDMS) in a Y-channel design that consisted of two generated magnetic fields: one localized below the channel, and an external field outside of the device generated through two rare earth magnets. The external field provided a method to attract the superparamagnetic beads while the localize field influenced attractive and replusive forces in the channel. The localized magnetic field allowed for controlling the direction the superparamagnetic beads in the channel to a predetermined well. The localized magnetic field generated a field of 5.7 x 10-3 mT. The fluid flow within the device was electroosmotically driven. The electroosmotic flow in the channel was 3.13x10-7 cm2/V s. The superparamagnetic bead traveled down the channel at 8.98 x 10-5 m/s. Beads were identified with Raman spectroscopy.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.