Date of Award

2026

Document Type

Doctor of Nursing Practice (DNP)

Degree Name

Doctor of Nursing Practice (DNP)

Department

Nursing

Committee Chair

Darlene Showalter

Committee Member

Tripp Nelson

Subject(s)

Septicemia--Diagnosis, Septicemia--Treatment, Pregnancy--Complications--Diagnosis, Pregnancy--Complications, Obstetrical emergencies, Medical protocols

Abstract

Obstetric sepsis is a disease that can be deadly and progress rapidly in patients. Sepsis is a leading cause of death in pregnancy, and many of these deaths have been deemed as preventable. Normal physiological changes of pregnancy make diagnosing sepsis challenging, and sepsis screening tools for the general adult population are not reliable in obstetric patients. Obstetric sepsis is an emergency and needs rapid recognition and treatment. At a large academic medical center, there was no obstetric sepsis screening tool or protocol, so sepsis was generally diagnosed in a pregnant or postpartum patient late in the infection cycle, and the rate of obstetric sepsis in the facility was significantly higher than the national average. An evidence-based obstetric sepsis care bundle was implemented in a high-risk, high-volume obstetric emergency department, utilizing a modified pregnancy screening tool, a treatment algorithm, and a provider order set. A total of 50 health care providers and registered nurses working in the obstetrical emergency department implemented the obstetric sepsis care bundle. 1300 women were screened using the pregnancy-modified screening tool, and compliance with screening ranged from 70-75% for the duration of the project, pointing to the sustainability of this project. 24 women screened positive, and the entire bundle was implemented, with 90% of lab draws and antibiotic administration falling within the benchmark time of 60 minutes or less after a positive screen. Implementation of this care bundle has increased clinicians’ awareness of obstetric sepsis and facilitated equitable care by facilitating non-objective, inclusive screening and uniform treatment if warranted.

Available for download on Thursday, November 04, 2027

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